Comparing safety of abrasion and tape-stripping as skin preparation in allergen-specific epicutaneous immunotherapy
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منابع مشابه
Comparing safety of abrasion and tape-stripping as skin preparation in allergen-specific epicutaneous immunotherapy.
Unspecified DOI: 10.1016/j.jaci.2014.07.037 Posted at the Zurich Open Repository and Archive, University of Zurich ZORA URL: http://doi.org/10.5167/uzh-108857 Originally published at: von Moos, Seraina; Johansen, Pål; Tay, Fabian; Graf, Nicole; Kündig, Thomas M; Senti, Gabriela (2014). Comparing safety of abrasion and tape-stripping as skin preparation in allergen-specific epicutaneous immunoth...
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BACKGROUND Epicutaneous immunotherapy targets the network of dendritic cells in the epidermis. Allergen exposure of the dermal layers should be limited as these contain mast cells and blood vessels, which increases the risk for local and systemic allergic reactions. METHODS This intraindividually controlled trial included 20 subjects with birch pollen allergy. Three areas of the volar forearm...
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The results of our third trial on epicutaneous allergen-specific immunotherapy (EPIT) will be presented and discussed in the context of our previous trials. This monocentric, placebo-controlled, double-blind phase I/IIa trial included 98 patients with grass pollen rhinoconjunctivitis. Prior to the pollen season 2009, patients received six patches (allergen extract: n = 48; placebo: n = 50) with...
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Epicutaneous immunotherapy onto intact skin has proved to be an efficient and safe alternative treatment of allergy in an animal model with various allergens and in children for cow's milk allergy. The aim of this study was to analyze the different steps of the immunological handling of the allergen when deposited on intact skin using an epicutaneous delivery system and its immune consequences ...
متن کاملRecent Progress in Allergen Immunotherapy
The efficacy of allergen immunotherapy for the treatment of allergic rhinoconjunctivitis with or without seasonal bronchial asthma and anaphylaxis caused by the sting of the hymenoptera class of insects has been clearly demonstrated in numerous well-designed, placebo-controlled trials. Immunotherapy whether by subcutaneous injection of allergen extract or by oral/sublingual routes modifies peri...
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ژورنال
عنوان ژورنال: Journal of Allergy and Clinical Immunology
سال: 2014
ISSN: 0091-6749
DOI: 10.1016/j.jaci.2014.07.037